vascular pathology in benign HT
hyaline arteriosclerosis
- pink, homogenous hyaline thickening
- leakeage of plasma protein across endothelial cells
- production of excessive ECM by smooth ms cells
vascular pathology in malignant HT
hyperplastic arteriosclerosis
- onionskin, concentric, laminated smooth ms with progressive narrowing of lumen
- thickening of the smooth ms cells
- reduplication of basement membrane
- accompanied by fibroid necrosis (pink appearance, severely damaged small arteries and arterioles)
HT can lead to
- atherosclerotis
- aneurysm of bv
- dissecting aneurysm
*source: lecture notes
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